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dc.contributor.advisorMartínez López, Carmen Alodia
dc.contributor.authorZambrano Lehericith, Kelly Johana
dc.contributor.authorMuegues Maestre, Hilda Rosa
dc.contributor.authorPérez Bonilla, Maria Fernanda
dc.date.accessioned2021-12-14T16:56:53Z
dc.date.available2021-12-14T16:56:53Z
dc.date.issued2021-12-14
dc.identifier.citationZambrano, K,J, Muegues, H,R y Pérez,M,F (2021). Rendimiento diagnóstico de las muestras de saliva para detectar SARS-CoV2: umbrella review [Tesis de Pregrado] Universidad Santo Tomas, Bucaramanga, Colombia.spa
dc.identifier.urihttp://hdl.handle.net/11634/38713
dc.descriptionIntroducción: Existe una necesidad clínica e investigativa en el campo de la salud relacionado con pruebas para la detección del virus SARS-Cov2. En la búsqueda, se pretende minimizar: protocolo de toma de muestra, costos e incomodidades de examen. Muestras de saliva, han sido protocolizadas, como medio diagnóstico para este fin. Objetivo: realizar un estudio tipo Umbrella Review para evaluar el rendimiento diagnóstico de las pruebas para determinar SARS-Cov2 por medio de saliva, así como también su efectividad clínica, siendo evaluada según la evidencia científica por medio de publicaciones de estudios tipo revisiones sistemáticas y metaanálisis. Materiales y métodos: Se ejecutó una exhaustiva búsqueda bibliográfica por medio de ecuaciones de búsqueda en las bases de datos PubMed, Embase, Scielo, Scopus y Google académico donde se consideraron publicaciones de los años 2020 y 2021. Inicialmente se recuperaron un total de 216 artículos y tras su filtrado, donde se tuvo en cuenta criterios de inclusión y exclusión como año de publicación, idioma y tema de interés quedaron 13 estudios recuperados para su respectivo análisis por medio de la aplicación de la lista de chequeo AMSTAR. Resultados: se obtuvo que las pruebas de detección del virus SARS-Cov2 por medio de muestras de saliva, tienen en promedio una sensibilidad que oscila entre un 80-97.7% (95% CI, 0.83–0.89) y una especificidad entre 95-97% (95% CI: 89.5–98.8). los valores de sensibilidad y especificidad de la prueba NPS y Saliva son relativamente similares para casos sintomáticos con alta carga viral y bastante aceptables para pacientes asintomáticos con baja carga viral Conclusión: Estos resultados, demostraron que las pruebas por medio de muestras de saliva tienen una alta precisión y efectividad diagnostica para la detección del virus SARS-Cov2 siempre y cuando sean pruebas de saliva con aclarado faríngeospa
dc.description.abstractThere is a clinical and research need in the health field for tests for the detection of the SARS-Cov2 virus. In the search, it is intended to minimize sampling protocol, examination costs and discomfort. Saliva samples have been protocolized as a diagnostic means for this purpose. Objective: to carry out an Umbrella Review type study to evaluate the diagnostic performance of the tests to determine SARS-Cov2 through saliva, as well as its clinical effectiveness, being evaluated according to scientific evidence through publications of studies such as systematic reviews and meta-analyzes. Materials and methods: An exhaustive bibliographic search was carried out using search equations in the PubMed, Embase, Scielo, Scopus and academic Google databases, where publications from the years 2020 and 2021 were considered. Initially, a total of 216 articles were retrieved. and after filtering, where inclusion and exclusion criteria were considered, such as year of publication, language, and topic of interest, 13 studies were retrieved for their respective analysis through the application of the AMSTAR checklist. Results: it was obtained that the SARS-Cov2 virus detection tests through saliva samples have an average sensitivity that ranges between 80-97.7% (95% CI, 0.83-0.89) and a specificity between 95-97 % (95% CI: 89.5–98.8). the sensitivity and specificity values ​​of the NPS and Saliva test are relatively similar for symptomatic cases with high viral load and quite acceptable for asymptomatic patients with low viral load. Conclusion: These results demonstrated that tests using saliva samples have a high diagnostic accuracy and effectiveness for the detection of the SARS-Cov2 virus if they are tests of saliva with pharyngeal rinsing.spa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.publisherUniversidad Santo Tomásspa
dc.titleRendimiento diagnóstico de las muestras de saliva para detectar SARS-CoV2: umbrella reviewspa
dc.typebachelor thesis
dc.description.degreenameOdontólogospa
dc.publisher.programPregrado Odontologíaspa
dc.publisher.facultyFacultad de Odontologíaspa
dc.subject.keywordSalivaspa
dc.subject.keywordSARS-CoV-2spa
dc.subject.keywordCOVID-19.spa
dc.subject.keywordDiagnostic testspa
dc.subject.lembSalivaspa
dc.subject.lembInfecciones por coronavirusspa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembInfecciones respiratoriasspa
dc.subject.lembDiagnóstico virológicospa
dc.type.localTesis de pregradospa
dc.rights.localAbierto (Texto Completo)spa
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.coverage.campusCRAI-USTA Bucaramangaspa
dc.description.domainhttps://www.ustabuca.edu.co/spa
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dc.contributor.corporatenameUniversidad Santo Tomásspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2
dc.subject.proposalSalivaspa
dc.subject.proposalSARS-CoV-2spa
dc.subject.proposalCOVID-19.spa
dc.subject.proposalPruebas diagnósticasspa
dc.identifier.reponamereponame:Repositorio Institucional Universidad Santo Tomásspa
dc.identifier.instnameinstname:Universidad Santo Tomásspa
dc.type.categoryFormación de Recurso Humano para la Ctel: Trabajo de grado de Pregradospa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1f
dc.description.degreelevelPregradospa
dc.identifier.repourlrepourl:https://repository.usta.edu.cospa
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driveinfo:eu-repo/semantics/bachelorThesis


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