Evaluación histológica y clínica del efecto cicatrizante del propóleo: revisión sistemática

Abstract

Propolis is formed by resinous substances and beeswax Apis mellifera. Its healing property has not been clearly defined. Objective: To demonstrate the healing property of propolis through a systematic review. Assess the quality of the items with the CONSORT and analyze the activity of publication by bibliometric indicators. Materials and methods: 5 databases available at the University St. Thomas to find articles that have been conducted experimental studies or clinical trials evaluating the effect of propolis in the healing process. Results: 97.6% of the items reported favorable results. Only 3 items were human clinical trials and meet 28.6% of the CONSORT items. Most articles published in the last five years led by 2013. Over 90% of the articles are in English. PubMed and Scopus were the foundations that contributed more articles. The country where more has been published is Brazil. Conclusions: Propolis is a substance that clearly influences the healing process. 97.6% of the evaluated items reported to have had positive results when valued the substance in animals models, human or invitro.