Synthesis and X-ray diffraction data of 2-ethyl-6-(pyridin-4-yl)-7H-indeno [2,1-c]quinoline

Camargo, H.A.Sánchez, A.Henao, J.A.Romero Bohórquez, Arnold R.Kouznetsov, Vladimir V.2020-01-172020-01-172014-03http://hdl.handle.net/11634/20710The compound 2-ethyl-6-(pyridin-4-yl)-7H-indeno[2,1-c]quinoline (2) (chemical formula C23H22N2) was synthesized through the free-solvent oxidation reaction mediated by elemental sulfur from the corresponding 2-ethyl-6-(pyridin-4-yl)-5,6,6a,11b-tetrahidro-7H-indeno[2,1-c]quinoline (1), an adduct easily obtained, using the Lewis acid-promoted [4 + 2] cycloaddition reaction. Preliminary molecular characterization was performed by Fourier transform-infrared and gas chromatographymass spectrometry. The X-ray powder diffraction (XRPD) pattern for the title compound was analyzed and found to be crystallized in monoclinic system, space group P21/n (N° 14) with refined unit-cell parameters a = 20.795 (8) Å, b = 7.484 (2) Å, c = 10.787 (2) Å and ß = 93.96° (2). The volume of the unit cell is V = 1674.8 (6) Å3 .application/pdfAtribución-NoComercial-CompartirIgual 2.5 Colombiahttp://creativecommons.org/licenses/by-nc-sa/2.5/co/Synthesis and X-ray diffraction data of 2-ethyl-6-(pyridin-4-yl)-7H-indeno [2,1-c]quinolineindeno[2, 1-c]quinolinesAntitumoral activityX-ray powder diffractionhttps://doi.org/10.1017/S0885715613000730Generación de Nuevo Conocimiento: Artículos publicados en revistas especializadas - Electrónicos