Castillo, John J.Rozo, Ciro E.Castillo-León, JaimeRindzevicius, TomasSvendsen, Winnie E.Rozlosnik, NoemiBoisen, AnjaMartínez, Fernando2020-01-222020-01-222013-02-18http://hdl.handle.net/11634/21042This Letter involved the preparation of a conjugate between single-walled carbon nanotubes and folic acid that was obtained without covalent chemical functionalization using a simple ‘one pot’ synthesis method. Subsequently, the conjugate was investigated by a computational hybrid method: our own Nlayered Integrated Molecular Orbital and Molecular Mechanics (B3LYP(6–31G(d):UFF)). The results confirmed that the interaction occurred via hydrogen bonding between protons of the glutamic moiety from folic acid and p electrons from the carbon nanotubes. The single-walled carbon nanotube-folic acid conjugate presented herein is believed to lead the way to new potential applications as carbon nanotubebased drug delivery systems.application/pdfAtribución-NoComercial-CompartirIgual 2.5 Colombiahttp://creativecommons.org/licenses/by-nc-sa/2.5/co/Folic acidCarbon nanotubesMolecular mechanicsMolecular orbitalhttps://doi.org/10.1016/j.cplett.2013.02.014Generación de Nuevo Conocimiento: Artículos publicados en revistas especializadas - Electrónicos