Puerto Galvis, Carlos E.Vargas Méndez, Leonor Y.Kouznetsov, Vladimir V.2020-01-222020-01-222013-06-28http://hdl.handle.net/11634/21011Chemical and pharmacological information on cantharidin-based SMs was analyzed. The review summarizes new facts about blister beetles metabolites for the period 2006-2012. General synthetic approaches to cantharidin-based small molecules as well as its chemical transformations and the biological activities related with cantharidin, norcantharidin, cantharidimide and norcantharimide analogues, specially their inhibitory activity of phosphoprotein phosphatases in cancer treatment, were discussed in this mini review that could help to design new small molecules modulators for other biological models.application/pdfAtribución-NoComercial-CompartirIgual 2.5 Colombiahttp://creativecommons.org/licenses/by-nc-sa/2.5/co/Cantharidin analoguesBlister beetlesPP inhibitory activityAnticancer activityDielsAlder cycloaddition reactionsDrug design and developmenthttps://doi.org/10.1111/cbdd.12180Generación de Nuevo Conocimiento: Artículos publicados en revistas especializadas - Electrónicos