Análisis estadístico de los factores de riesgo que inciden en la adquisición de tos ferina en recién nacidos de la ciudad de Bogotá

Abstract

At the global level, great technological advances have made possible the increase of scientific studies, for the improvement of human health. Hence, many of these studies are focused on the analysis of the efficiency and effectiveness of some vaccines, which help to mitigate symptoms or prevent diseases. Specifically, the District Health Secretary is interested in determining the ability of pregnant mothers to develop antibodies against whooping cough and the transmissibility of these to the newborn in order to prevent it from catching the disease in its _rst trimester of life. In the present investigation, we propose a method for the identi_cation of the threshold of seroconversion in mothers, the threshold of transmissibility to the newborn and the threshold to identify the loss of antibodies in newborns. Finally, the factors associated with the production of antibodies in the mother and the transmission of these to the newborn were identi_ed using gamma regression models.