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Abordajes terapéuticos farmacológicos avanzados para las alteraciones de la superficie ocular en diabetes mellitus tipo 1 y tipo 2: revisión exploratoria de la literatura
(Universidad Santo Tomás, 2026-10-29) Serna Morales, Nataly; Narvaez Rumie, Olivia Margarita; Universidad Santo Tomás
Objective: To describe advanced pharmacological therapeutic approaches for ocular surface alterations in patients with type 1 and type 2 diabetes mellitus, as reported in the literature. Methods: An exploratory literature review was conducted on advanced pharmacological therapeutic approaches for ocular surface disorders associated with type 1 and type 2 diabetes mellitus. The databases PubMed, Scopus, ScienceDirect, SciELO, and Google Scholar were searched. Publications from the previous ten years in English and Spanish were considered, and predefined inclusion and exclusion criteria were applied. Data from the selected studies were organized in an extraction matrix to characterize the publications, identify the therapies evaluated, and synthesize the reported clinical outcomes. Results: A total of 27 studies were included in the exploratory review. The identified therapeutic approaches included topical immunomodulators, such as cyclosporine A and lifitegrast; secretagogues, such as diquafosol and rebamipide; and blood-derived biological therapies, including autologous serum, platelet-rich plasma (PRP), and plasma rich in growth factors (PRGF). The studies reported favorable outcomes in several ocular surface parameters, including dry eye symptoms, tear film stability, corneal staining, and epithelial repair. However, a substantial proportion of the therapeutic evidence came from studies involving patients with dry eye disease who were not specifically selected for diabetes mellitus, limiting the extent to which these benefits can be directly attributed to the diabetic population. Conclusions: The exploratory review identified several advanced pharmacological therapeutic approaches for managing ocular surface disorders. The included studies reported benefits across different clinical parameters; however, evidence specifically involving patients with diabetes mellitus was limited. Further clinical research focused on this population is needed to establish the efficacy and safety of the identified therapies more precisely.
Propuesta de un modelo de indicadores clave para la optimización de la productividad y el control de costos en el transporte terrestre de carga de POMAR-SABANALAC
(Universidad Santo Tomás, 2026-10-29) Matallana Estupiñan, Jhurixsa Alexandra; Poveda Jaimes, Oscar Fabian; Flórez Orejuela, Edwuin Andrés; Universidad Santo Tomás
POMAR-SABANALAC faces challenges in measuring productivity and controlling costs in its road freight transportation operations due to the lack of key performance indicators (KPIs) to assess operational efficiency, optimize resource utilization, and support strategic decision-making. The objective of this research is to propose a key performance indicator model to improve productivity and control costs associated with the company’s transportation operations. The study adopted a quantitative approach, with a descriptive scope and a proposal-oriented component, through a documentary review of scientific literature, applicable regulations, and management models, complemented by an analysis of the company’s operational and administrative information. Due to the partial availability of data provided by the company, a reference operational scenario incorporating simulated data was developed to illustrate the application of the model. As a result, a set of indicators was structured into three dimensions: operational productivity, cost control, and profitability. The proposed indicators include cost per kilometer traveled, fleet utilization, fuel consumption, delivery compliance, and operational profitability. It is concluded that the proposed model provides a tool to support logistics performance monitoring, identify improvement opportunities, and enhance managerial decision-making. However, its effectiveness will depend on the quality and availability of information, organizational commitment, and the continuous monitoring of the established indicators.
Por las sendas de la historia de nuestras ideas, en diálogo con la tradición filosófica latinoamericana
(Universidad Santo Tomás, 2026-10-29) Díaz Guzmán, Omar David; Arpini, Adriana María; Universidad Santo Tomás; https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001754193; https://scholar.google.com/citations?user=ieUZmKoAAAAJ&hl=es; https://scholar.google.com/citations?user=NO1eke4AAAAJ&hl=es; https://scienti.minciencias.gov.co/gruplac/jsp/visualiza/visualizagr.jsp?nro=00000000000851; https://orcid.org/0000-0001-7351-780X; https://orcid.org/0000-0002-5459-0363
This work comprises two fundamental stages. The first arises from a meticulous study by Omar David Díaz Guzmán, in which he reconstructs the methodological shifts of figures such as Arturo Andrés Roig, Francisco Miró Quesada, and Enrique Dussel. Drawing on Dussel’s work, we propose a periodization that allows us to reflect on our history of ideas. In the second part, we examine the reflections of the Argentine philosopher in dialogue with thinkers from "Our America." It is illuminating to understand the proposals, tensions, expansions, and reductions that have shaped our history of ideas—informed by debates involving Augusto Salazar Bondy, Francisco Romero, Arturo Andrés Roig, and Francisco Miró Quesada, as well as philosophies of liberation, a decisive element in addressing the challenges of contemporary philosophy. This work contributes to Latin American philosophy by granting us access to the intersection of the history of ideas and the philosophy of liberation. From this vantage point, we can map the generations and approaches that have sought our identity—and move beyond it—ultimately grasping that the history of ideas is not merely an account of the past, but a form of vital knowledge.
Propuesta para la creación de una asociación de recolectores de café en el municipio de Floridablanca, Santander
(Universidad Santo Tomás, 2026-10-29) Hernández Anaya, Alberto; Bayona Soto, José Andrés; Universidad Santo Tomás
This pre-project proposal aims to lay the groundwork for creating an association of coffee pickers in the municipality of Floridablanca, Santander, in response to seasonal labor shortages and the labor informality that characterizes this activity. The specific objectives are to socioeconomically characterize the coffee pickers of the municipality; to design a proposed organizational structure, positions, functions, processes and procedures for the future association; and to describe the legal and tax aspects required for its incorporation. A descriptive, cross-sectional approach with qualitative interpretive support is proposed, using a non-probability convenience sampling design targeting a minimum of 30 pickers linked to the coffee-growing villages of the municipality, through a structured survey instrument. The study is articulated with the USTAGRI research group's territorial rural development line and with Sustainable Development Goals 1, 8 and 10. The findings are expected to lay the groundwork for an associative model that dignifies labor, improves pickers' income and strengthens the competitiveness of coffee farming in the region.
Estrategia de internacionalizacion del turismo en el departamento del Amazonas: innovacion tecnologica para el acceso a mercados globales
(Universidad Santo Tomás, 2026-10-29) Diaz Triana, Diana Valentina; Zambrano Valdivieso, Oscar Javier; Universidad Santo Tomas
Nature tourism in the Amazonas department represents an opportunity to strengthen territorial development, sustainability, and the destination’s participation in international markets. However, the region faces challenges related to connectivity, infrastructure, digital promotion, and service quality. Therefore, this research aimed to design an internationalization strategy for Amazonian tourism based on technological innovation. The study was conducted using a qualitative approach, combining a documentary review with exploratory empirical validation through the analysis of academic sources, institutional reports, technical documents, official statistics, and input from tourism service providers. The findings made it possible to identify the main conditions of the Amazonian tourism system, recognize technologies applicable to the region, analyze adoption barriers, and propose innovation mechanisms to strengthen tourism promotion, commercialization, and management. Based on these findings, a strategic roadmap was designed to improve connectivity, digital transformation, tourism intelligence, international commercialization, and sustainability. The study concludes that the internationalization of Amazonian tourism should be understood as a gradual process of capacity building, in which technology can facilitate access to international markets, increase visitor confidence, and enhance the destination’s competitiveness, provided that its implementation is adapted to the territory’s conditions and needs.