ASSOCIATION BETWEEN CIGARETTE AND ALCOHOL CONSUMPTION IN PREGNANT AS A RISK FACTOR FOR NON-SYNDROMIC CLEFT LIP AND/OR PALATE

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https://revistas.ustabuca.edu.co/index.php/USTASALUD_ODONTOLOGIA/article/view/1121
10.15332/us.v11i2.1121
10.15332/us.v11i2.1121
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Universidad Santo Tomás Seccional Bucaramanga
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Objetivo: determinar la asociación entre el consumo de cigarrillo y alcohol en la mujer embarazada como factor de riesgo para labio y/o paladar hendido no sindrómico e hipodoncia.Materiales y métodos: se realizó un estudio de corte trasversal con una muestra de 79 pacientes entre los 4 y 18 años que habían sido diagnosticados con labio y/o paladar hendido no sindrómico. Se realizó una encuesta a las madres, se diligenció el formulario del Estudio Colaborativo Latinoamericano de Malformaciones Congénitas (ECLAM) y se tomó una radiografía panorámica a los pacientes. Se realizó un análisis descriptivo, se usó la prueba de Chi2 y Test exacto de Fisher para las variables cualitativas y t de Student o U. de Mann Whitney para las cuantitativas. Una regresión logística determinó la asociación entre las variables consumo de cigarrillo y alcohol con la presencia de labio y/o paladar hendido no sindrómico. Se consideró un valor alpha igual a 0,05.Resultados: el 96% de la población estudiada presentó labio y/o paladar hendido, relacionándose con el lado en que el paciente tenía la hipodoncia, que se presentó en el 85% de la muestra. En los pacientes con labio y paladar hendido se encontró hipodoncia en el 85% de los casos, la hipodoncia del incisivo lateral superior es la más frecuente en el 81% de los casos, seguido de la hipodoncia de premolares, en el 7% de los casos. El 35% de las madres presentó antecedente de fumadora y el 43% acostumbraba a tomar alcohol. Se encontró que las mujeres en embarazo que habían consumido alcohol tenían una probabilidad 1,5 veces de tener un hijo/a con labio y/o paladar hendido aunque este valor no fue estadísticamente significativo [OR 1,5 IC 95% 0,13 – 17,66].Conclusiones: al determinar la asociación entre el consumo de cigarrillo y alcohol como factor de riesgo en labio y paladar hendido, no se encontró una relación estadísticamente significativa, pero sí una relación positiva entre las variables mencionadas.[Torres EA, Gómez G, Pinzón Z. Asociación entre el consumo de cigarrillo y alcohol en la gestante como factor de riesgo para labio y/o paladar hendido no sindrómico. Ustasalud 2012; 11: 88 - 94]
Objective: to assess the association between cigarette smoking and alcohol consumption in pregnant women as a risk factor for cleft lip and / or nonsyndromic cleft palate and hypodontia.Methods: a cross-sectional study was done with a sample of 79 patients between 4 and 18 years who had been diagnosed with nonsyndromic cleft lip and/or cleft palate. We conducted a survey of mothers, the form from Latin American Collaborative Study of Congenital Malformations (ECLAM) was filled out and a panoramic x-ray was taken for every patient. We performed a descriptive analysis, we used the Chi2 test and Fisher exact test for qualitative variables and Student t test or U. Mann Whitney test for quantitative variables. A logistic regression determined the association between the variables smoking and alcohol consumption in the presence of lip and / or non-syndromic cleft palate. An alpha value equal to 0.05 was considered.Results: 96% of the studied population had lip and/or cleft palate, interacting with the side on which the patient had hypodontia, which was present in 85% of the sample. Hypodontia was found in 85% of the patients with cleft lip, with the upper lateral incisor hypodontia most prevalent in 81% of cases, followed by hypodontia of premolars in 7% of the cases. The 35% of the mothers presented a history of smoking and 43% used to drink alcohol. It was found that pregnant women who consumed alcohol were 1.5 times likely to have a son / daughter with cleft lip and/or palate although this value was not statistically significant [OR 1.5, 95% CI 0.13 - 17.66].Conclusions: there was no statistically significant value to determine the association between cigarette smoking and alcohol as a risk factor for cleft lip and palate but a positive relationship between these variables was found.
Objective: to assess the association between cigarette smoking and alcohol consumption in pregnant women as a risk factor for cleft lip and / or nonsyndromic cleft palate and hypodontia.Methods: a cross-sectional study was done with a sample of 79 patients between 4 and 18 years who had been diagnosed with nonsyndromic cleft lip and/or cleft palate. We conducted a survey of mothers, the form from Latin American Collaborative Study of Congenital Malformations (ECLAM) was filled out and a panoramic x-ray was taken for every patient. We performed a descriptive analysis, we used the Chi2 test and Fisher exact test for qualitative variables and Student t test or U. Mann Whitney test for quantitative variables. A logistic regression determined the association between the variables smoking and alcohol consumption in the presence of lip and / or non-syndromic cleft palate. An alpha value equal to 0.05 was considered.Results: 96% of the studied population had lip and/or cleft palate, interacting with the side on which the patient had hypodontia, which was present in 85% of the sample. Hypodontia was found in 85% of the patients with cleft lip, with the upper lateral incisor hypodontia most prevalent in 81% of cases, followed by hypodontia of premolars in 7% of the cases. The 35% of the mothers presented a history of smoking and 43% used to drink alcohol. It was found that pregnant women who consumed alcohol were 1.5 times likely to have a son / daughter with cleft lip and/or palate although this value was not statistically significant [OR 1.5, 95% CI 0.13 - 17.66].Conclusions: there was no statistically significant value to determine the association between cigarette smoking and alcohol as a risk factor for cleft lip and palate but a positive relationship between these variables was found.
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Orofacial cleft, Smoking, Anodontia, Risk factor, Labio leporino, Hábito de fumar, Anodoncia
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