Factores de riesgo maternos y ambientales relacionados con el labio leporino y/o paladar hendido no sindrómico en una población atendida por el posgrado de ortodoncia de la universidad Santo Tomás

Abstract

The objective of this investigation was to determine the maternal and environmental risk related factors for non syndromic lip and / or cleft palate in a population served by the Orthodontics residents at the Santo Tomás university. 42 cases and 84 controls patients served by the residents at the Floridablanca headquarters Orthodontics University of Santo Tomás were taken. A survey was conducted to the mothers of children with and without CLP. Started getting the patients medical history out of the university files, then the patients were cited and surveyed. Univariate analysis allowed us to establish the general characteristics of the studied population, then another bivariate analysis was performed to determine the statistically significant variables. Finally a multivariate analysis was done. The findings in this study allowed us to establish risk factors that increase the likelihood of of CLP appearance. These risk factors include: belonging to a socioeconomic stratum 1 or 2 with an OR 2.64, the presence of family history of CLP with an OR of 13.6, abortion history with an OR of 2.96, fumigation storage elements increases the risk with an OR of 4.70; spraying activities with an OR of 4.70 and exposure to pesticides during the first trimester of pregnancy with an OR of 5.25. The low strata (1 and 2), history of abortion, fumigation storage and activities, exposure to pesticides and fungicides and family and herediatry aspects proved to be risk factors associated with the presence of CLP.