Evaluación de la susceptibilidad y resistencia de larvas de aedes aegypti a metabolitos secundarios de plantas aromáticas y medicinales

Abstract

Vector-borne diseases account for more than 17% of all infectious diseases. (World Health Organization, 2016). In tropical countries aedes aegypti is responsible for the transmission of yellow fever, the Dengue virus, the Chikungunya virus, and the Zika virus, among others. There is little known about these diseases and how to treat them, for this reason, it is necessary to control the population of vectors. Currently, the control of these is done through the use of chemical compounds from the organophosphorus family, which, due to their massive use, are generating resistance to these compounds. In this investigation the susceptibility of Aedes aegypti larvae of two strains, Rockefeller and Piedecuesta, against insecticides of natural and synthetic origin was determined, applying the methodology proposed by the WHO of 26 chemical entities, terpenoid compounds, essential oils and insecticides. . With the above results, the resistance of the vectors to all the compounds was calculated, in order to find new useful compounds for the effective control of the vector. Among the metabolites studied are different terpenes, monoterpenes, phenylpropanoids, among others.