Actividad larvicida y efecto residual de piperidinas e insecticidas organofosforados en las proteínas de Aedes aegypti (Díptera: Culicidae)

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dc.contributor.advisorVargas Méndez, Leonor Yamile
dc.contributor.authorTorres Reyes, Erika Amparo
dc.date.accessioned2021-03-16T20:40:39Z
dc.date.available2021-03-16T20:40:39Z
dc.date.issued2021-03-15
dc.descriptionEn esta investigación se determinó la actividad la susceptibilidad y resistencia de las larvas en tercer instar del mosquito Aedes aegypti de la cepa Piedecuesta (colectada en campo), y la cepa Rockefeller a los insecticidas malatión, clorpirifos, y temefos, y a 16 derivados piperidínicos. A ambas cepas se le cuantificaron las proteínas totales y las colinesterasas. A las larvas previamente expuestas a una concentración sub-letal de los insecticidas, se les determinó la actividad colinérgica residual, y el tipo de inhibición causada sobre la AChE. Los resultados mostraron la cepa silvestre fue altamente resistente a malatión y clorpirifos, y que catorce de las piperidinas evaluadas son una alternativa promisoria para controlar las poblaciones de larvas por su elevada toxicidad, comportándose como inhibidores colinérgicos de tipo mixto.spa
dc.description.abstractThe purpose of this research was to determine the activity, susceptibility, and resistance of larvae on third instar of mosquito Aedes aegypti to insecticides known as Malathion, Chlorpyrifos, and Temephos, as well as to 16 piperidine derivates. To accomplish the purpose of this study, Piedecuesta strain (collected in the field) and Rockefeller strain were used. In both cases, the total proteins and cholinesterase rates were quantified. In the case of the larvae that had been previously exposed to sublethal concentration of the insecticides, residual cholinergic activity was determined, as well as the type of inhibition caused by the AChE. The results of the research showed that the wild-type strain was highly resistant to Malathion and Chlorpyrifos; it was also registered that 14 of the tested piperidines, by acting as mixed-type cholinergic inhibitors, are a promising alternative to control the populations of larvae due to their high toxicity.spa
dc.description.degreelevelMaestríaspa
dc.description.degreenameMagister en Ciencias y Tecnologías Ambientalesspa
dc.description.domainhttps://www.ustabuca.edu.co/spa
dc.format.mimetypeapplication/pdf
dc.identifier.citationTorres-Reyes, E. A. (2021). Actividad larvicida y efecto residual de piperidinas e insecticidas organofosforados en las proteínas de Aedes aegypti (Díptera: Culicidae). [Tesis de maestría]. Universidad Santo Tomás, Bucaramanga, Colombiaspa
dc.identifier.instnameinstname:Universidad Santo Tomásspa
dc.identifier.reponamereponame:Repositorio Institucional Universidad Santo Tomásspa
dc.identifier.repourlrepourl:https://repository.usta.edu.cospa
dc.identifier.urihttp://hdl.handle.net/11634/32506
dc.language.isospa
dc.publisherUniversidad Santo Tomásspa
dc.publisher.branchCRAI-USTA Bucaramangaspa
dc.publisher.facultyFacultad de Química Ambientalspa
dc.publisher.programMaestría Ciencias y Tecnologías Ambientalesspa
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dc.rights.accessrightsinfo:eu-repo/semantics/closedAccess
dc.rights.coarhttp://purl.org/coar/access_right/c_14cb
dc.rights.localAcceso cerradospa
dc.subject.keywordAedes aegyptispa
dc.subject.keywordAcetylcholinesterasespa
dc.subject.keywordEnzymatic activityspa
dc.subject.keywordOrganophosphatespa
dc.subject.keywordPiperidinesspa
dc.subject.lembPiperidinasspa
dc.subject.lembInsecticidasspa
dc.subject.lembCompuestos organofosforadosspa
dc.subject.lembMosquitosspa
dc.subject.lembInsectos vectoresspa
dc.subject.lembLarvas de insectosspa
dc.subject.lembEnzimas - Análisisspa
dc.subject.lembAcetilcolinesterasaspa
dc.subject.proposalAedes aegyptispa
dc.subject.proposalAcetilcolinesterasaspa
dc.subject.proposalExpresión enzimáticaspa
dc.subject.proposalOrganofosforadosspa
dc.subject.proposalPiperidinasspa
dc.titleActividad larvicida y efecto residual de piperidinas e insecticidas organofosforados en las proteínas de Aedes aegypti (Díptera: Culicidae)spa
dc.typemaster thesis
dc.type.categoryFormación de Recurso Humano para la Ctel: Trabajo de grado de Maestríaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.driveinfo:eu-repo/semantics/masterThesis
dc.type.localTesis de maestríaspa
dc.type.versioninfo:eu-repo/semantics/acceptedVersion

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