Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos
| dc.contributor.advisor | Osorio Martínez, Carlos Alberto | |
| dc.contributor.author | Pinzón Troncoso, Jennifer Alejandra | |
| dc.date.accessioned | 2024-05-08T18:38:15Z | |
| dc.date.available | 2024-05-08T18:38:15Z | |
| dc.date.issued | 2024-05-08 | |
| dc.description | La contaminación del agua es un problema serio para la salud y el medio ambiente, lo que hace crucial monitorear su calidad. Los métodos tradicionales como la espectroscopia de absorción atómica y la espectrometría de plasma son efectivos pero costosos y lentos. En respuesta, se han desarrollado métodos fluorogénicos y cromogénicos que ofrecen una alternativa rápida y eficiente para detectar trazas de iones metálicos en solución. Estos sensores, en particular los que tienen propiedades de fluorescencia, son valorados por su especificidad y sensibilidad, siendo ideales para uso en áreas remotas. Este estudio avanza en el desarrollo de sensores ópticos fluorescentes, y describe la síntesis de nuevos compuestos tipo heptanoides β-dicarbonílicos, similares a la curcumina, pero más efectivos en detectar iones metálicos. Estos compuestos muestran propiedades fluorescentes al reaccionar con metales de transición, ofreciendo nuevas posibilidades para la detección de contaminantes. La caracterización de estos sensores se realiza mediante técnicas avanzadas como la espectroscopía infrarroja y la resonancia magnética nuclear, y se evalúa su eficacia y toxicidad mediante espectrofotometría ultravioleta-visible y pruebas ecotoxicológicas en bulbos de cebolla. | spa |
| dc.description.abstract | Water pollution is a serious issue for human health and the environment, making it crucial to monitor water quality. Traditional methods such as atomic absorption spectroscopy and plasma spectrometry are effective but costly and slow. In response, fluorogenic and chromogenic methods have been developed, offering a rapid and efficient alternative for detecting traces of metal ions in solution. These sensors, particularly those with fluorescence properties, are valued for their specificity and sensitivity, making them ideal for use in remote areas. This study advances the development of fluorescent optical sensors and describes the synthesis of new heptanoid β-diketone compounds, like curcumin but more effective in detecting metal ions. These compounds exhibit fluorescent properties when reacting with transition metals, offering new possibilities for pollutant detection. The characterization of these sensors is carried out using advanced techniques such as infrared spectroscopy and nuclear magnetic resonance, and their efficacy and toxicity are assessed through ultraviolet-visible spectrophotometry and ecotoxicological tests on onion bulbs. | spa |
| dc.description.degreelevel | Pregrado | spa |
| dc.description.degreename | Químico Ambiental | spa |
| dc.description.domain | https://www.ustabuca.edu.co/ | spa |
| dc.format.mimetype | application/pdf | |
| dc.identifier.citation | Pinzón Troncoso, J.A. (2024). Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos. [Trabajo de pregrado]. Universidad Santo Tomás, Bucaramanga, Colombia | spa |
| dc.identifier.instname | instname:Universidad Santo Tomás | spa |
| dc.identifier.reponame | reponame:Repositorio Institucional Universidad Santo Tomás | spa |
| dc.identifier.repourl | repourl:https://repository.usta.edu.co | spa |
| dc.identifier.uri | http://hdl.handle.net/11634/55061 | |
| dc.language.iso | spa | |
| dc.publisher | Universidad Santo Tomás | spa |
| dc.publisher.branch | CRAI-USTA Bucaramanga | spa |
| dc.publisher.faculty | Facultad de Química Ambiental | spa |
| dc.publisher.program | Pregrado Química Ambiental | spa |
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| dc.relation.references | Tabanelli, R.; Brogi, S.; Calderone, V. (2021). Improving Curcumin Bioavailability: Current Strategies and Future Perspectives. Pharmaceutics. 13(10). 1715. https://doi.org/10.3390/pharmaceutics13101715 | spa |
| dc.relation.references | Trivedi, P., & Axe, L. (2000). Modeling Cd and Zn sorption to hydrous metal oxides. Environ. Sci. Technol. 34(11). 2215–2223. https://doi.org/10.1021/es991110c | spa |
| dc.relation.references | Tsuda, T. (2018). Curcumin as a functional food-derived factor: Degradation products, metabolites, bioactivity, and future perspectives. Food Funct. 9. 705–714. https://doi.org/10.1039/C7FO01242J | spa |
| dc.relation.references | Vonnie, J.M.; Ting, B.J.; Rovina, K.; Erna, K.H.; Felicia,W.X.L.; ‘Aqilah, N.M.N.;Wahab, R.A.(2022). Development of Aloe Vera-Green Banana Saba-Curcumin Composite Film for Colorimetric Detection of Ferrum (II). Polymers. 14(12). 2353. https://doi.org/10.3390/polym14122353 | spa |
| dc.relation.references | Wang, B., Wang, L., Chen, Ch., Zhang, Y., Gao, J., Lu, K., Yan,Ch., Nan, G., Li, Y. (2023). A Review on Recent Advances in Peptide-based Fluorescence Probes and their Potential Applications. 8(31). e202302216. https://doi.org/10.1002/slct.202302216 | spa |
| dc.relation.references | Wang, Y., Wang, J-K., Alkhazragi, O., Gutiérrez-Arzaluz, L., Zhang, H., Kang, Ch-H., Khee Ng, T., Bakr, O.M., Mohammed, O.F., Ooi, B.S. (2023). Multifunctional difluoroboron β-diketonate-based luminescent receiver for a high-speed underwater wireless optical communication system. Optics Express. 31(20). 32516-32528. https://doi.org/10.1364/OE.500330 | spa |
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| dc.relation.references | Xu, H., Zhang, W., Wang, M. (2022). Bioinspired Fluorescent Polymers: Synthesis, Processing, and Applications. Chinese Journal of Chemistry. 41(4). 458-468. https://doi.org/10.1002/cjoc.202200493 | spa |
| dc.relation.references | Yang, D., Liu, Y., Geng, J., Kou, X., Xin, Z., Lv, M. (2018). Engineering nanomaterials-based biosensors for food safety detection. Biosens. Bioelectron. 106, 122–128. https://doi.org/10.1016/j.bios.2018.01.049 | spa |
| dc.relation.references | Zacharioudaki, D-E., Fitilis, I., Kotti, M. (2022). Review of Fluorescence Spectroscopy in Environmental Quality Applications. Molecules, 27(15), 4801. https://doi.org/10.3390/molecules27154801 | spa |
| dc.relation.references | Zainab, A., Rooh Ullah, M., Tuzen, S-U., Rahim, A., Tawfik, A-S.. (2023). Colorimetric sensing of heavy metals on metal doped metal oxide nanocomposites: A review, Trends in Environmental Analytical Chemistry. 37. e00187. https://doi.org/10.1016/j.teac.2022.e00187. | spa |
| dc.relation.references | Zhang, Y., Khan, A.R., Fu, M., Zhai, Y., Yu, A., Zha, G. (2019) The progresses in curcuminoids-based metal complexes: especially in cancer therapy. Future Medicinal Chemistry. 11(9). 1035–1056. https://doi.org/10.4155/fmc-2018-0190. | spa |
| dc.rights | Atribución-NoComercial-SinDerivadas 2.5 Colombia | |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
| dc.rights.local | Abierto (Texto Completo) | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
| dc.subject.keyword | Fluorescent sensors | spa |
| dc.subject.keyword | Chemosensors | spa |
| dc.subject.keyword | Curcumin analogs | spa |
| dc.subject.keyword | Transition metals | spa |
| dc.subject.lemb | Espectrometría | spa |
| dc.subject.lemb | Detección de contaminantes | spa |
| dc.subject.lemb | Espectroscopia Infrarroja | spa |
| dc.subject.lemb | Espectrofotometría de ultravioleta visible | spa |
| dc.subject.lemb | Pruebas ecotoxicológicas | spa |
| dc.subject.proposal | Sensores fluorescentes | spa |
| dc.subject.proposal | Análogos de curcumina | spa |
| dc.subject.proposal | Quimiosensores | spa |
| dc.subject.proposal | Metales de transición | spa |
| dc.title | Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos | spa |
| dc.type.category | Formación de Recurso Humano para la Ctel: Trabajo de grado de Pregrado | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | |
| dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | |
| dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | |
| dc.type.drive | info:eu-repo/semantics/bachelorThesis | |
| dc.type.local | Trabajo de grado | spa |
| dc.type.version | info:eu-repo/semantics/acceptedVersion |
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