Capítulo 7. Aplicación del método voltamétrico en uno de los analgésicos más vendidos: Paracetamol
dc.contributor.advisor | Cabeza, Ivan | |
dc.contributor.author | Molano Hoyos, Jose Daniel | |
dc.contributor.corporatename | Politécnico Gran Colombiano | spa |
dc.contributor.corporatename | Universidad Santo Tomás | spa |
dc.coverage.campus | CRAI-USTA Bogotá | spa |
dc.date.accessioned | 2021-04-22T17:36:00Z | |
dc.date.available | 2021-04-22T17:36:00Z | |
dc.date.issued | 2021-04-21 | |
dc.description | Los medicamentos con el pasar de los años se han vuelto indispensables en la vida del ser humano ya que ayudan con distintos problemas enfocados a la salud. Sin embargo estos se consideran contaminantes emergentes debido a que son compuestos los cuales no han sido clasificados oficialmente como generadores de contaminación pero que si la generan. En este capítulo analizaremos uno de los analgésicos más vendidos que es el paracetamol, el cual posee propiedades antipiréticas y analgésicas lo que hace que se encargue de aliviar dolores musculares, fiebre, dolores de cabeza, etc, haciendo que este sea uno de los más utilizados en casas u hospitales dando así alta contaminación potencial de cuerpos de agua y por ende uno de los contaminantes con mayores concentraciones en el ambiente; resultando en aguas residuales tanto domésticas como industriales. Existe un método analítico avanzado el cual es de mayor acceso que la mayoría llamado electroquímica la cual se fundamenta en la medición de una magnitud de corriente, carga y potencial a través de la electrolisis. Uno de sus métodos es la voltametria la cual se ha utilizado para la determinación de sustancias orgánicas e inorgánicas en muestras ambientales. En este capitulo se hablara de como se ha utilizado para la determinación de paracetamol y los resultados que se han generado. | spa |
dc.description.abstract | Medications over the years have become essential in the life of the human being since they help with different problems focused on health. However, these are considered emerging pollutants because they are compounds which have not been officially classified as pollution generators but do generate it. In this chapter we will analyze one of the best-selling analgesics that is paracetamol, which has antipyretic and analgesic properties which makes it responsible for relieving muscle aches, fever, headaches, etc., making this one of the most used in homes or hospitals thus giving high potential contamination of bodies of water and therefore one of the pollutants with the highest concentrations in the environment; resulting in both domestic and industrial wastewater. There is an advanced analytical method which is more accessible than most called electrochemistry which is based on the measurement of a magnitude of current, charge and potential through electrolysis. One of its methods is voltammetry which has been used for the determination of organic and inorganic substances in environmental samples. In this chapter we will talk about how it has been used for the determination of paracetamol and the results that have been generated. | spa |
dc.description.degreelevel | Pregrado | spa |
dc.description.degreename | Ingeniero Ambiental | spa |
dc.description.domain | http://unidadinvestigacion.usta.edu.co | spa |
dc.format.mimetype | application/pdf | spa |
dc.identifier.citation | Molano Hoyos, J. D. (2021). Capitulo 7. Aplicación del método voltamétrico en uno de los analgésicos más vendidos: Paracetamol.[Trabajo de pregrado, Universidad Santo Tomás]. Repositorio Institucional. | spa |
dc.identifier.instname | instname:Universidad Santo Tomás | spa |
dc.identifier.reponame | reponame:Repositorio Institucional Universidad Santo Tomás | spa |
dc.identifier.repourl | repourl:https://repository.usta.edu.co | spa |
dc.identifier.uri | http://hdl.handle.net/11634/33696 | |
dc.language.iso | spa | spa |
dc.publisher | Universidad Santo Tomás | spa |
dc.publisher.faculty | Facultad de Ingeniería Ambiental | spa |
dc.publisher.program | Pregrado de Ingeniería Ambiental | spa |
dc.relation.references | Acevedo-Barrios, R. L., Severiche-Sierra, C. A. y Jaimes Morales, Jose Del Carmen. (2017). Efectos tóxicos del paracetamol en la salud humana y el ambiente. Revista De Investigación Agraria Y Ambiental, 8(1), 139-149. https://doi.org/10.22490/21456453.1845 | spa |
dc.relation.references | Adelaide, M., (2009). Capítulo 10 técnicas electroquímicas para la determinación y especiación de arsénico en aguas. | spa |
dc.relation.references | Aguilar, A., Ascitelli, A., Carosella, L., Izurieta, M., Perandones, M., Soverchia, S., . . . Scublinsky, D. (2015). Prevalencia de automedicación de antiinflamatorios y analgésicos en la práctica ambulatoria. Universidad de Buenos Aires. | spa |
dc.relation.references | Akhter, S., Basirun, W. J., Alias, Y., Johan, M. R., Bagheri, S., Shalauddin, M., Ladan, M., y Anuar, N. S. (2018). Enhanced amperometric detection of paracetamol by immobilized cobalt ion on functionalized MWCNTs - Chitosan thin film. Analytical Biochemistry, 551, 29-36. https://doi.org/10.1016/j.ab.2018.05.004 | spa |
dc.relation.references | Amare, M. (2019). Voltammetric determination of paracetamol in tablet formulation using Fe (III) doped zeolite-graphite composite modified GCE. Heliyon, 5(5), e01663. https://doi.org/10.1016/j.heliyon.2019.e01663 | spa |
dc.relation.references | Azab, S. M. (2019). A comprehensive structural comparison between cellulose and starch polymers functionalized cobalt nanoparticles sensors for the nanomolar detection of paracetamol. Journal of Electroanalytical Chemistry, 840, 319-327. https://doi.org/10.1016/j.jelechem.2019.04.011 | spa |
dc.relation.references | Bayram, E., & Akyilmaz, E. (2016). Development of a new microbial biosensor based on conductive polymer/multiwalled carbon nanotube and its application to paracetamol determination. Sensors and Actuators. B, Chemical, 233, 409-418. doi:10.1016/j.snb.2016.04.029 | spa |
dc.relation.references | Bosch, M. E., Sánchez, A. J. R., Rojas, F. S. y Ojeda, C. B. (2006). Determination of paracetamol: Historical evolution. Journal of Pharmaceutical and Biomedical Analysis, 42(3), 291-321. https://doi.org/10.1016/j.jpba.2006.04.007 | spa |
dc.relation.references | Burç, M., Köytepe, S., Duran, S. T., Ayhan, N., Aksoy, B., y Seçkin, T. (2020). Development of voltammetric sensor based on polyimide-MWCNT composite membrane for rapid and highly sensitive detection of paracetamol. Measurement : Journal of the International Measurement Confederation, 151, 107103. https://doi.org/10.1016/j.measurement.2019.107103 | spa |
dc.relation.references | Camargo, J. R., Andreotti, I. A. A., Kalinke, C., Henrique, J. M., Bonacin, J. A., y Janegitz, B. C. (2020). Waterproof paper as a new substrate to construct a disposable sensor for the electrochemical determination of paracetamol and melatonin. Talanta, 208, 120458. https://doi.org/10.1016/j.talanta.2019.120458 | spa |
dc.relation.references | Chen, Y., Zheng, G., Shi, Q., Zhao, R., y Chen, M. (2018). Preparation of thiolated calix[8]arene/AuNPs/MWCNTs modified glassy carbon electrode and its electrocatalytic oxidation toward paracetamol. Sensors and Actuators. B, Chemical, 277, 289-296. https://doi.org/10.1016/j.snb.2018.09.012 | spa |
dc.relation.references | Dhanush, S., Sreejesh, M., Bindu, K., Chowdhury, P., y Nagaraja, H. S. (2018). Synthesis and electrochemical properties of silver dendrites and silver dendrites/rGO composite for applications in paracetamol sensing. Materials Research Bulletin, 100, 295-301. https://doi.org/10.1016/j.materresbull.2017.12.044 | spa |
dc.relation.references | Doğan, B., Elik, A., y Altunay, N. (2020). Determination of paracetamol in synthetic urea and pharmaceutical samples by shaker-assisted deep eutectic solvent microextraction and spectrophotometry. Microchemical Journal, 154, 104645. https://doi.org/10.1016/j.microc.2020.104645 | spa |
dc.relation.references | Du. H, Xie. Y. y Wang. J. (2021). Nanomaterial-sensors for herbicides detection using electrochemical techniques and prospect applications. Trends in Analytical Chemistry. https://doi.org/10.1016/j.trac.2020.116178. | spa |
dc.relation.references | Duncan C.W. y Watson D.P.B. (2008). Diagnosis and management of headache in adults: summary of SIGN guideline, BMJ 337. http://dx.doi.org/10.1136/bmj.a2329. | spa |
dc.relation.references | EL Bouabi, Y., Farahi, A., Labjar, N., El Hajjaji, S., Bakasse, M., y El Mhammedi, M. A. (2016). Square wave voltammetric determination of paracetamol at chitosan modified carbon paste electrode: Application in natural water samples, commercial tablets and human urines. Materials Science and Engineering: C, 58, 70-77. https://doi.org/10.1016/j.msec.2015.08.014 | spa |
dc.relation.references | Gil, M. J., Adriana, /., Soto, M., Jorge, /., Usma, I., & Darío Gutiérrez, O. (2012). Emerging contaminants in waters: Effects and possible treatments contaminantes emergentes em águas, efeitos e possíveis tratamentos | spa |
dc.relation.references | Hodgman, M. y Garrard, A. (2012). A Review of Acetaminophen Poisoning. Rev Critical Care Clinics. 28(4): 499-516. | spa |
dc.relation.references | Hoeger, B., Köllner, B., Dietrich, D. R., & Hitzfeld, B. (2005). Water-borne diclofenac affects kidney and gill integrity and selected immune parameters in brown trout ( salmo trutta f. fario). Aquatic Toxicology, 75(1), 53-64. doi:10.1016/j.aquatox.2005.07.006 | spa |
dc.relation.references | Hudec, R., Božeková, L., y Tisoňová, J. (2012). Consumption of three most widely used analgesics in six European countries. Journal of Clinical Pharmacy and Therapeutics, 37(1), 78-80. https://doi.org/10.1111/j.1365-2710.2011.01256.x | spa |
dc.relation.references | Ikehata, K., Jodeiri Naghashkar, N., & Gamal El-Din, M. (2006). Degradation of aqueous pharmaceuticals by ozonation and advanced oxidation processes: A review. Ozone: Science & Engineering, 28(6), 353-414. doi:10.1080/01919510600985937 | spa |
dc.relation.references | Kang, X., Wang, J., Wu, H., Liu, J., Aksay, I. A., y Lin, Y. (2010). A graphene-based electrochemical sensor for sensitive detection of paracetamol. Talanta (Oxford), 81(3), 754-759. https://doi.org/10.1016/j.talanta.2010.01.009 | spa |
dc.relation.references | Khaskheli, A. R., Fischer, J., Barek, J., Vyskočil, V., Sirajuddin, & Bhanger, M. I. (2013). Differential pulse voltammetric determination of paracetamol in tablet and urine samples at a micro-crystalline natural graphite–polystyrene composite film modified electrode. Electrochimica Acta, 101, 238-242. doi:10.1016/j.electacta.2012.09.102 | spa |
dc.relation.references | Kissinger, P. T., y Heineman, W. R. (1983). Cyclic Voltammetry. Journal of Chemical Education, 60(9), 702-706. DOI: 10.1021/ed060p702 | spa |
dc.relation.references | KRISHNAN, A. V., STATHIS, P., PERMUTH, S. F., TOKES, L., & FELDMAN, D. (1993). Bisphenol-A: An estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology (Philadelphia), 132(6), 2279-2286. doi:10.1210/en.132.6.2279 | spa |
dc.relation.references | Kumar, N., Bhadwal, A. S., Mizaikoff, B., Singh, S., y Kranz, C. (2019). Electrochemical detection and photocatalytic performance of MoS2/TiO2 nanocomposite against pharmaceutical contaminant: Paracetamol. Sensing and Bio-Sensing Research, 24, 100288. https://doi.org/10.1016/j.sbsr.2019.100288 | spa |
dc.relation.references | Kumar, Y., Pramanik, P., y Das, D. K. (2019). Electrochemical detection of paracetamol and dopamine molecules using nano-particles of cobalt ferrite and manganese ferrite modified with graphite. Heliyon, 5(7), e02031. https://doi.org/10.1016/j.heliyon.2019.e02031 | spa |
dc.relation.references | Li, Y., Feng, S., Li, S., Zhang, Y., y Zhong, Y. (2014). A high effect polymer-free covalent layer by layer self-assemble carboxylated MWCNTs films modified GCE for the detection of paracetamol. Sensors & Actuators: B. Chemical, 190, 999-1005. https://doi.org/10.1016/j.snb.2013.09.052 | spa |
dc.relation.references | Mancipe, L. C., Fernández A, D. C. y Fernández A, D. G. (2010). INTOXICACIÓN POR ACETAMINOFÉN. Revista Med, 18(2), 221-227. http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-52562010000200008&lng=en&tlng=en | spa |
dc.relation.references | Masutani, H. (2001). Oxidative stress and redox imbalance in acetaminophen toxicity, Pharmacogenomics J. 1, 165–166. http://dx.doi.org/10.1038/sj.tpj.6500036. | spa |
dc.relation.references | Niedziałkowski, P., Cebula, Z., Malinowska, N., Białobrzeska, W., Sobaszek, M., Ficek, M., Bogdanowicz, R., Anand, J. S., y Ossowski, T. (2019). Comparison of the paracetamol electrochemical determination using boron-doped diamond electrode and boron-doped carbon nanowalls. Biosensors and Bioelectronics, 126, 308-314. https://doi.org/10.1016/j.bios.2018.10.063 | spa |
dc.relation.references | Nikolaou, A., Meric, S., & Fatta, D. (2007). Occurrence patterns of pharmaceuticals in water and wastewater environments. Analytical and Bioanalytical Chemistry, 387(4), 1225-1234. doi:10.1007/s00216-006-1035-8 | spa |
dc.relation.references | Patil, M. M., Shetti, N. P., Malode, S. J., Nayak, D. S. y Chakklabbi, T. R. (2019). Electroanalysis of paracetamol at nanoclay modified graphite electrode. Materials Today: Proceedings, 18, 986-993. https://doi.org/10.1016/j.matpr.2019.06.538 | spa |
dc.relation.references | Quesada Penate, I., Jauregui Haza, U. J., Wilhelm, A. y Delmas, H. (2009). Contaminación de las aguas con productos farmacéuticos. Estrategias para enfrentar la problemática. Revista de ciencias biológicas, 40(3), 173. | spa |
dc.relation.references | Skoog, D. A. y West, D. M. (2014). Voltametría. En A. Orozco. (Ed.), Fundamentos de química analítica (pp. 610-645). Cengage Learning. | spa |
dc.relation.references | Song, Y., Zhang, Y., Li, J., Tan, C., y Li, Y. (2020). Preparation of poly ionic liquid-mesoporous carbon nanospheres and its application in simultaneous determination of hydroquinone and catechol, and detection of paracetamol. Journal of Electroanalytical Chemistry (Lausanne, Switzerland), 865, 114157. https://doi.org/10.1016/j.jelechem.2020.114157 | spa |
dc.relation.references | Tejada, C., Quiñonez, E., y Peña, M. (2014). Contaminantes Emergentes en Aguas: Metabolitos de Fármacos. Una Revisión. Revista Facultad De Ciencias Básicas, 10(1), 80. https://doi.org/10.18359/rfcb.341 | spa |
dc.relation.references | Weber, F., Grüttner, G., Bergmann, A., Carius, A., y Beek, T. A. (2016). Pharmaceuticals in the environment: Global occurrence and potential cooperative action under the strategic approach to international chemicals management (SAICM) German Environment Agency. doi:10.4126/frl01-006401194 | spa |
dc.relation.references | Yang, L., Yu, L. E. y Ray, M. B. (2009). Photocatalytic Oxidation of Paracetamol: Dominant Reactants, Intermediates, and Reaction Mechanisms. Environmental Science & Technology, 43(2), 460-465. https://doi.org/10.1021/es8020099 | spa |
dc.rights | Atribución-NoComercial-SinDerivadas 2.5 Colombia | * |
dc.rights | Atribución-NoComercial-SinDerivadas 2.5 Colombia | * |
dc.rights.accessrights | info:eu-repo/semantics/closedAccess | |
dc.rights.coar | http://purl.org/coar/access_right/c_14cb | |
dc.rights.local | Acceso cerrado | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | * |
dc.subject.keyword | Emerging pollutant | spa |
dc.subject.keyword | Paracetamol | spa |
dc.subject.keyword | Electrochemical determination | spa |
dc.subject.keyword | Health damage | spa |
dc.subject.keyword | Water contamination | spa |
dc.subject.keyword | Contamination through human and animal excrement | spa |
dc.subject.lemb | Analgésicos | spa |
dc.subject.lemb | Medicamentos | spa |
dc.subject.lemb | Cuidado del medioambiente | spa |
dc.subject.lemb | Contaminación del agua | spa |
dc.subject.proposal | Contaminante emergente | spa |
dc.subject.proposal | Paracetamol | spa |
dc.subject.proposal | Determinación electroquímica | spa |
dc.subject.proposal | Daños en la salud | spa |
dc.subject.proposal | Contaminación por exccrementos humanos y animales | spa |
dc.title | Capítulo 7. Aplicación del método voltamétrico en uno de los analgésicos más vendidos: Paracetamol | spa |
dc.type | bachelor thesis | |
dc.type.category | Formación de Recurso Humano para la Ctel: Trabajo de grado de Pregrado | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | |
dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | |
dc.type.drive | info:eu-repo/semantics/bachelorThesis | |
dc.type.local | Tesis de pregrado | spa |
dc.type.version | info:eu-repo/semantics/acceptedVersion |
Archivos
Bloque original
1 - 3 de 3

- Nombre:
- 2021josemolano.pdf
- Tamaño:
- 754.39 KB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Trabajo de Grado

- Nombre:
- Carta aprobacion facultad autoarchivo JOSE DANIEL MOLANO HOYOS.pdf
- Tamaño:
- 300.75 KB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Carta aprobación facultad

- Nombre:
- CARTA DERECHOS DE AUTOR CRAI JOSE DANIEL MOLANO HOYOS.pdf
- Tamaño:
- 206.66 KB
- Formato:
- Adobe Portable Document Format
- Descripción:
- Carta derechos de autor
Bloque de licencias
1 - 1 de 1

- Nombre:
- license.txt
- Tamaño:
- 807 B
- Formato:
- Item-specific license agreed upon to submission
- Descripción: