Cantharidin-based small molecules as potential therapeutic agents

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dc.contributor.authorPuerto Galvis, Carlos E.
dc.contributor.authorVargas Méndez, Leonor Y.
dc.contributor.authorKouznetsov, Vladimir V.
dc.date.accessioned2020-01-22T17:21:07Z
dc.date.available2020-01-22T17:21:07Z
dc.date.issued2013-06-28
dc.description.abstractChemical and pharmacological information on cantharidin-based SMs was analyzed. The review summarizes new facts about blister beetles metabolites for the period 2006-2012. General synthetic approaches to cantharidin-based small molecules as well as its chemical transformations and the biological activities related with cantharidin, norcantharidin, cantharidimide and norcantharimide analogues, specially their inhibitory activity of phosphoprotein phosphatases in cancer treatment, were discussed in this mini review that could help to design new small molecules modulators for other biological models.spa
dc.description.domainhttp://unidadinvestigacion.usta.edu.cospa
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/cbdd.12180spa
dc.identifier.urihttp://hdl.handle.net/11634/21011
dc.publisher.branchCRAI-USTA Bogotáspa
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dc.rightsAtribución-NoComercial-CompartirIgual 2.5 Colombia
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/2.5/co/
dc.subject.keywordCantharidin analoguesspa
dc.subject.keywordBlister beetlesspa
dc.subject.keywordPP inhibitory activityspa
dc.subject.keywordAnticancer activityspa
dc.subject.keywordDielsAlder cycloaddition reactionsspa
dc.subject.keywordDrug design and developmentspa
dc.titleCantharidin-based small molecules as potential therapeutic agentsspa
dc.type.categoryGeneración de Nuevo Conocimiento: Artículos publicados en revistas especializadas - Electrónicosspa

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