Evaluación de la extracción de principios activos de ortiga (Urtica dioica) y agraz (Vaccinium meridionale) mediante el uso de hidrocavitación
| dc.contributor.author | Malagón Romero, Dionisio Humberto | |
| dc.contributor.author | Forero Rubiano, Ricardo Alberto | |
| dc.contributor.author | Nausa Galeano, Gloria Astrid | |
| dc.contributor.cvlac | http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000167061 | |
| dc.contributor.cvlac | http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001094947 | |
| dc.contributor.cvlac | http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000013766 | |
| dc.contributor.googlescholar | https://scholar.google.com/citations?user=b0ldFjcAAAAJ&hl=es&oi=ao | |
| dc.contributor.googlescholar | https://scholar.google.com/citations?user=&user=EyAX1aEAAAAJ | |
| dc.contributor.googlescholar | https://scholar.google.es/citations?hl=es&user=lmHQtNkAAAAJ | |
| dc.contributor.orcid | https://orcid.org/0000-0003-2890-2180 | |
| dc.contributor.orcid | https://orcid.org/0000-0001-7683-3541 | |
| dc.contributor.orcid | https://orcid.org/0000-0002-5905-6151 | |
| dc.date.accessioned | 2020-04-20T16:24:05Z | |
| dc.date.available | 2020-04-20T16:24:05Z | |
| dc.date.issued | 2019-08 | |
| dc.description | Colombia cuenta con condiciones geográficas privilegiadas, gracias a lo cual, tiene una gran variedad de especies vegetales disponibles. Sin embargo, la mayoría de los productos obtenidos a partir de estas suelen tener una baja transformación y por ende bajo valor agregrado. El presente proyecto pretende obtener extractos naturales de dos plantas, ortiga (Urtica dioica) y agraz (Vaccinium meridionale), las cuales son ampliamente cultivadas en el país y que tienen una gran proyección para la formulación de productos en las industrias alimenticia, cosmética y farmacéutica. Para tal fin, se evaluará la hidrocavitación como método novedoso de extracción, que no ha sido reportado hasta el momento en la literatura y con el que la Universidad Santo Tomás cuenta, gracias al desarrollo propiciado en la Facultad de Ingeniería Mecánica. Entendiendo que el presente proyecto cubre únicamente la primera etapa, la obtención de los extractos, este será el punto de partida para la futura formulación de productos con alto valor agregado. | spa |
| dc.description.abstract | Colombia has privileged geographical conditions, thanks to which, it has a great variety of available plant species. However, most of the products obtained from them usually have a low transformation and therefore low added value. This project aims to obtain natural extracts from two plants, nettle (Urtica dioica) and agraz (Vaccinium meridionale), which are widely cultivated in the country and which have a great projection for the formulation of products in the food, cosmetic and pharmaceutical industries. . For this purpose, hydrocavitation will be evaluated as a novel extraction method, which has not been reported in the literature so far and which the Universidad Santo Tomás has, thanks to the development promoted at the Faculty of Mechanical Engineering. Understanding that the present project covers only the first stage, obtaining the extracts, this will be the starting point for the future formulation of products with high added value. | spa |
| dc.description.domain | http://unidadinvestigacion.usta.edu.co | spa |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://hdl.handle.net/11634/22618 | |
| dc.publisher.branch | CRAI-USTA Bogotá | spa |
| dc.relation.references | Basso, L. A. et al. The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases - A Review. Mem. Inst. Oswaldo Cruz 100, 475–506 (2005). | spa |
| dc.relation.references | Berkem. Plant extraction - Berkem - Extraction végétale. Available at: http://www.berkem.com/en/expertise-en/plant-extraction. (Accessed: 29th July 2019) | spa |
| dc.relation.references | S. Sasidharan, Y. Chen, D. Saravanan, K.M. Sundram, L. Y. L. EXTRACTION, ISOLATION AND CHARACTERIZATION OF BIOACTIVE COMPOUNDS FROM PLANTS’ EXTRACTS. Afr J Tradit Complement Altern Med 8, 93–130 (2011). | spa |
| dc.relation.references | ogate, P. R. & Pandit, A. B. A review and assessment of hydrodynamic cavitation as a technology for the future. Ultrason. Sonochem. 12, 21–27 (2005) | spa |
| dc.relation.references | Sampath Kumar, K. & Moholkar, V. S. Conceptual design of a novel hydrodynamic cavitation reactor. Chem. Eng. Sci. 62, 2698–2711 (2007). | spa |
| dc.relation.references | Vitenko, T., Droździel, P. & Rudawska, A. Using Hydrodynamic Cavitation Device in the Industry. Adv. Sci. Technol. Res. J. 12, 158–167 (2018) | spa |
| dc.relation.references | Ghayal, D., Pandit, A. B. & Rathod, V. K. Optimization of biodiesel production in a hydrodynamic cavitation reactor using used frying oil. Ultrason. Sonochem. 20, 322–328 (2013). | spa |
| dc.relation.references | Suslick, K. S., Mdleleni, M. M. & Ries, J. T. Chemistry induced by hydrodynamic cavitation. J. Am. Chem. Soc. (1997). doi:10.1021/ja972171i | spa |
| dc.relation.references | Beattie, A. J. et al. CH. 10 New Products and Industries from Biodiversity. Ecosyst. Hum. Well-Being Curr. State Trends 273–295 (2005). | spa |
| dc.relation.references | Niño, J., Mosquera, O. M. & Correa, Y. M. Antibacterial and antifungal activities of crude plant extracts from Colombian biodiversity. Rev. Biol. Trop. 60, 1535–1542 (2012). | spa |
| dc.relation.references | Sharrock, S., Oldfield, S. & Wilson, O. Plant Conservation Report 2014: a review of progress towards the Global Strategy for Plant Conservation 2011-2020. CBD Technical Series (2014). | spa |
| dc.relation.references | BRAVO, K. & PEREAÑEZ, J. A. Colombian Biodiversity, an Opportunity for the Strengthening of the Pharmaceutical and Cosmetic Industries. Rev. Vitae 23, 163 (2017). | spa |
| dc.relation.references | Gyllenhaal, C., Quinn, M. Lou & Soejarto, O. O. Research on Colombian Medicinal Plants: Roles and Resources for Plant Taxonomists. Caldasia 15, 199–217 (1983). | spa |
| dc.relation.references | Holetz, F. B. et al. Screening Pl Medicinais 2.Pdf. 97, 1027–1031 (2002) | spa |
| dc.relation.references | Pretorius, J. C., Magama, S. & Zietsman, P. C. Growth inhibition of plant pathogenic bacteria and fungi by extracts from selected South African plant species. South African J. Bot. 69, 186–192 (2003). | spa |
| dc.relation.references | Newman, D. J. & Cragg, G. M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 70, 461–477 (2007). | spa |
| dc.relation.references | Universidad Nacional de. Agraz en polvo. Agencia de Noticias UN 1 (2017). | spa |
| dc.relation.references | Đurović, S. et al. Chemical composition of stinging nettle leaves obtained by different analytical approaches. J. Funct. Foods 32, 18–26 (2017) | spa |
| dc.relation.references | Salih, N. A. Effect of nettle (Urtica dioica) extract on gentamicin induced nephrotoxicity in male rabbits. Asian Pac. J. Trop. Biomed. (2015). doi:10.1016/j.apjtb.2015.07.005 | spa |
| dc.relation.references | Domínguez-Rodríguez, G., Marina, M. L. & Plaza, M. Strategies for the extraction and analysis of non-extractable polyphenols from plants. J. Chromatogr. A 1514, 1–15 (2017) | spa |
| dc.relation.references | Akalin, M. K., Karagöz, S. & Akyüz, M. Application of response surface methodology to extract yields from stinging nettle under supercritical ethanol conditions. J. Supercrit. Fluids (2013). doi:10.1016/j.supflu.2013.10.004 | spa |
| dc.relation.references | Di Virgilio, N. et al. The potential of stinging nettle (Urtica dioica L.) as a crop with multiple uses. Ind. Crops Prod. 68, 42–49 (2015). | spa |
| dc.relation.references | Vajić, U. J. et al. Optimization of extraction of stinging nettle leaf phenolic compounds using response surface methodology. Ind. Crops Prod. 74, 912–917 (2015). | spa |
| dc.relation.references | XU, C. C., WANG, B., PU, Y. Q., TAO, J. S. & ZHANG, T. Advances in extraction and analysis of phenolic compounds from plant materials. Chin. J. Nat. Med. 15, 721–731 (2017) | spa |
| dc.relation.references | Upton, R. Stinging nettles leaf (Urtica dioica L.): Extraordinary vegetable medicine. J. Herb. Med. (2013). doi:10.1016/j.hermed.2012.11.001 | spa |
| dc.relation.references | Zenão, S., Aires, A., Dias, C., Saavedra, M. J. & Fernandes, C. Antibacterial potential of Urtica dioica and Lavandula angustifolia extracts against methicillin resistant Staphylococcus aureus isolated from diabetic foot ulcers. J. Herb. Med. 10, 53–58 (2017) | spa |
| dc.relation.references | Potoroko, I. et al. Possibilities of Regulating Antioxidant Activity of Medicinal Plant Extracts. Human. Sport. Med. 17, 77–90 (2019). | spa |
| dc.relation.references | Ince, A. E., Sahin, S. & Sumnu, G. Comparison of microwave and ultrasound-assisted extraction techniques for leaching of phenolic compounds from nettle. J. Food Sci. Technol. 51, 2776–2782 (2014) | spa |
| dc.relation.references | Sajfrtová, M., Sovová, H., Opletal, L. & Bártlová, M. Near-critical extraction of β-sitosterol and scopoletin from stinging nettle roots. J. Supercrit. Fluids (2005). doi:10.1016/j.supflu.2004.12.008 | spa |
| dc.relation.references | Nencu, I. et al. THE SELECTION OF TECHNOLOGICAL PARAMETERS IN ORDER TO OBTAIN AN EXTRACT WITH IMPORTANT ANTIOXIDANT ACTIVITY FROM STINGING NETTLE LEAVES. 65, (2017) | spa |
| dc.relation.references | Celis, M. E. M., Tobón, Y. N. F., Agudeio, C., Arango, S. S. & Rojano, B. Andean berry (vaccinium meridionale swartz). in Fruit and Vegetable Phytochemicals: Chemistry and Human Health: Second Edition 2, 869–881 (2017) | spa |
| dc.relation.references | Forero Cabrera, N. M. Evaluación de parámetros de calidad físicos y químicos en agraz (Vaccinium meridionale Swartz) con el uso de espectroscopía de infrarrojo cercano – NIR. (Universidad Nacional de Colombia, 2017). | spa |
| dc.relation.references | Ministerio de Agricultura y Desarrollo Rural. Reporte: Área, Producción y Rendimiento Nacional por Cultivo. Agronet (2019). | spa |
| dc.relation.references | Garzón, G. A., Narváez, C. E., Riedl, K. M. & Schwartz, S. J. Chemical composition, anthocyanins, non-anthocyanin phenolics and antioxidant activity of wild bilberry (Vaccinium meridionale Swartz) from Colombia. Food Chem. 122, 980–986 (2010) | spa |
| dc.relation.references | López-Padilla, A. et al. Vaccinium meridionale Swartz extracts and their addition in beef burgers as antioxidant ingredient. J. Sci. Food Agric. (2018). doi:10.1002/jsfa.8483 | spa |
| dc.relation.references | Lopera, Y. E. et al. Antioxidant activity and cardioprotective effect of a nonalcoholic extract of Vaccinium meridionale Swartz during ischemia-reperfusion in rats. Evidence-based Complement. Altern. Med. 2013, (2013) | spa |
| dc.relation.references | Maldonado-Celis, M. E., Arango-Varela, S. S. & Rojano, B. A. Free radical scavenging capacity and cytotoxic and antiproliferative effects of Vaccinium meridionale Sw . agains colon cancer cell lines. Rev. Cuba. Plantas Med. 19, 172–184 (2014) | spa |
| dc.relation.references | Guzmán, M. & Cortázar, T. Inhibición de las actividades colagenasa y elastasa en fibroblastos humanos estimulados con UVB. Cosméticos Tecnol. Latinoamérica 2, 19–23 (2011) | spa |
| dc.relation.references | Martínez Zambrano, J. J., Rojas Sarmiento, H. A., Borda Guerra, G. del C., Hastamorir Caro, A. N. & Medina Riaño, M. F. Estabilidad de Antocianinas en Jugo y Concentrado de Agraz (Vaccinium meridionale Sw.). Rev. Fac. Nac. Agron. 64, 6015–6022 (2011 | spa |
| dc.relation.references | Bernal Roa, L. J. Evaluación de las Propiedades Bioactivas de Mora (Rubus glaucus) y Agraz (Vaccinium meridionale Swartz), en Fresco y Durante Procesos de Transformación. (Universidad Nacional de Colombia, 2012) | spa |
| dc.relation.references | Rutto, L. K., Xu, Y., Ramirez, E. & Brandt, M. Mineral properties and dietary value of raw and processed stinging nettle (Urtica dioica L.). Int. J. Food Sci. 2013, (2013) | spa |
| dc.relation.references | Yanza, E. G. & Maldonado, L. Y. Determinación del contenido de α-Tocoferol y β-Caroteno en el zumo y el liofilizado de tomate de arbol (Cyphomandra Betacea Cav Sendt ). Rev. la Fac. Ciencias Básicas 10, 28–35 (2012) | spa |
| dc.relation.references | AOAC. AOAC Official Method 2005.02 Total Monomeric Anthocyanin Pigment Content of Fruit Juices, Beverages, Natural Colorants, and Wines pH Differential Method. 2 (2006). | spa |
| dc.relation.references | Garzón, G. A., Narváez, C. E., Riedl, K. M. & Schwartz, S. J. Chemical composition, anthocyanins, non-anthocyanin phenolics and antioxidant activity of wild bilberry (Vaccinium meridionale Swartz) from Colombia. Food Chem. 122, 980–986 (2010). | spa |
| dc.rights | Atribución-NoComercial-SinDerivadas 2.5 Colombia | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
| dc.subject.keyword | Hydrocavitation | spa |
| dc.subject.keyword | Extraction | spa |
| dc.subject.keyword | Active principles | spa |
| dc.subject.keyword | Nettle | spa |
| dc.subject.keyword | Agraz | spa |
| dc.subject.proposal | Hidrocavitación | spa |
| dc.subject.proposal | Extracción | spa |
| dc.subject.proposal | Principios activos | spa |
| dc.subject.proposal | Ortiga | spa |
| dc.subject.proposal | Agraz | spa |
| dc.title | Evaluación de la extracción de principios activos de ortiga (Urtica dioica) y agraz (Vaccinium meridionale) mediante el uso de hidrocavitación | spa |
| dc.type.category | Formación de Recurso Humano para la Ctel: Proyecto ejecutado con investigadores en empresas, industrias y Estado | spa |
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