Evaluación de la Resistencia a Ceftriaxona, Amikacina y Oxacilina en Escherichia Coli Presente en Vertimientos de Agua Residual del Hospital de Suba II Nivel E.S.E. en Bogotá

Abstract

Pharmaceutical waste is transported to the water cycle by different routes, including wastewater treatment plant (WWTP), which act as a gateway for these products to bodies of water, because most of these compounds are not really held in their processes [1]. According to Vishal Diwan (2010), among these wastes, the presence of antibiotics has increased in aquatic ecosystems, implying that there is a significant impact on the development of resistance, toxicity in aquatic communities and therefore health public [2]. An assessment of the presence of bacterial resistance in the waste water of Suba’s Hospital was carried out using two different methods: diffusion method of Kirby - Bauer and dilution method in two samples of wastewater before the WWTP (AP) and two after the WWTP (DP); using three different antibiotics Amikacin (AMK), Ceftriaxone (CEF) and Oxacillin (OXA). According to the results it was determined that E. coli shows resistance to multiple antibiotics studied. Additionally it generated a greater resistance at DP because the inhibition zones were smaller. Considering the results of the Minimum Inhibitory Concentration (MIC), in the case of the AMK was obtained a MIC of 250 g/ml to AP and DP; in contrast to the CEF for DP the isolated bacteria increased by order of magnitude 33 g/ml to 333 g/ml. A similar result was presented at the OXA to AP with a MIC of 3330 g/ml and DP with 33300 g/ml.